From CorePy

CorePy supports many common ISAs and ISA extensions on Linux and OS X. The main CorePy features are supported on all platforms, but the Variable, Expression, and Iterator synthetic component frameworks are currently only implemented for PPC-based platforms.

	Operating Systems		CorePy Libraries
ISAs	Linux	OS X	Variables	Expressions	Iterators
PPC32	✓	✓	✓	✓	✓
PPC64	✓	✓	✓	✓	✓
VMX/AltiVec1	✓	✓	✓	✓	✓
Cell SPU	✓		✓	✓	✓
x862	✓	✓			✓
x86_642	✓	✓			✓
SSE3,4	✓	✓

1. VMX requires PPC32 or PPC64
2. The following legacy and OS-level instructions have not been implemented: 3DNow! extension, instructions using segment registers, and privileged instructions
3. SSE requires x86 or x86_64
4. Supported SSE versions are: SSE 1-3, SSSE3, SSE 4.1/4.2/4a

[edit] Known Working Platforms

CorePy has been tested and verified to work by the developers on the following platforms:

OS	CPU	Python
OS X 10.4	Intel Core Duo (x86)	2.3.5
OS X 10.5	PowerPC G5	2.5.1
OS X 10.5	Xeon 53XX (x86_64)	2.5.2
Linux	Xeon L5320 (x86_64)	2.4.3
Linux	Opteron 270 (x86_64)	2.4.3
Linux	Xeon (x86)	2.5.2
Linux	PowerPC Cell	2.5.1
Linux	Cell SPU	2.5.1